APPENDIX 1A Enzyme Nomenclature
Published Online: 1 MAY 2001
Copyright © 2003 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Pharmacology
How to Cite
2001. Enzyme Nomenclature. Current Protocols in Pharmacology. 00:1A:A.1A.1–A.1A.3.
- Published Online: 1 MAY 2001
- Published Print: MAR 1998
This appendix describes the “EC” (Enzyme Commission) numbering convention, starting with how enzymes are first grouped into one of six classes according to the reaction catalyzed, and then subclassified in terms of the donors, then acceptors, and then the actual enzyme reaction. An example is given of the major sub-subclasses of oxidoreductases along with many hundreds of enzymes in this class. Because this classification procedure came into being when there was little knowledge of enzyme structure and when protein cloning and expression was in its infancy, enzymes are classified according to their function. This is unlike receptor classification, which relies on structure and coupling.