APPENDIX 4B Guidelines for the Care and Use of Laboratory Animals in Biomedical Research

  1. Susan Jones-Bolin

Published Online: 1 DEC 2012

DOI: 10.1002/0471141755.pha04bs59

Current Protocols in Pharmacology

Current Protocols in Pharmacology

How to Cite

Jones-Bolin, S. 2012. Guidelines for the Care and Use of Laboratory Animals in Biomedical Research. Current Protocols in Pharmacology. 59:4B:A.4B.1–A.4B.9.

Author Information

  1. Thorndale, Pennsylvania

Publication History

  1. Published Online: 1 DEC 2012


This unit provides a general overview on topics related to the practical care and use of laboratory animals in biomedical research. These topics are briefly described and provide Web sites and/or research articles that can be accessed for more detailed information. While the primary focus is on the care and use of rats and mice bred for biomedical research, many of the Web sites listed provide information on other species used for this purpose. Curr. Protoc. Pharmacol. 59:A.4B.1-A.4B.9. © 2012 by John Wiley & Sons, Inc.


  • Animal Welfare Act;
  • Public Health Service (PHS) Policy;
  • IACUC;
  • ILAR;
  • guide;
  • OLAW (Office of Laboratory Animal Welfare);
  • animal housing and enrichment;
  • blood sampling;
  • compound administration;
  • animal numbers and group size;
  • pain recognition;
  • anesthesia;
  • analgesia;
  • euthanasia