UNIT 6.13 Synaptic Plasticity in the Hippocampal Slice Preparation
Published Online: 1 NOV 2001
Copyright © 2003 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Neuroscience
How to Cite
Bortolotto, Z. A., Anderson, W. W., Isaac, J. T. and Collingridge, G. L. 2001. Synaptic Plasticity in the Hippocampal Slice Preparation. Current Protocols in Neuroscience. 16:6.13:6.13.1–6.13.23.
- Published Online: 1 NOV 2001
- Published Print: AUG 2001
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Synaptic plasticity is the process by which the brain alters the strength of its synaptic connections, a fundamental function of the brain that enables individuals to learn from experience. The study of synaptic plasticity often involves the application of standard in vitro electrophysiological techniques to hippocampal slice preparations. This unit discusses many of the special considerations that are applicable for the optimal study of synaptic plasticity in this system. Most of these principles also apply to the study of synaptic plasticity in other brain slice preparations.