Unit

UNIT 6.18 Recording in the Cerebellar Slice

  1. Geoffrey T. Swanson1,
  2. Anis Contractor2

Published Online: 1 FEB 2004

DOI: 10.1002/0471142301.ns0618s25

Current Protocols in Neuroscience

Current Protocols in Neuroscience

How to Cite

Swanson, G. T. and Contractor, A. 2004. Recording in the Cerebellar Slice. Current Protocols in Neuroscience. 25:6.18:6.18.1–6.18.14.

Author Information

  1. 1

    University of Texas Medical Branch, Galveston, Texas

  2. 2

    The Salk Institute for Biological Studies, La Jolla, California

Publication History

  1. Published Online: 1 FEB 2004
  2. Published Print: OCT 2003

Abstract

This unit describes techniques for the preparation of mouse cerebellar slices and electrophysiological recording from neurons in the slice. The cerebellum provides a model of motor learning that can be correlated with alterations in synaptic function. In addition, the architecture and well-defined synaptic pathways in the cerebellar slice make this preparation a useful model for exploring general principles of synaptic transmission.

Keywords:

  • cerebellum;
  • synaptic transmission;
  • Purkinje cells;
  • granule cells;
  • deep cerebellar nuclei;
  • synaptic plasticity