UNIT 6.20 Caged Molecules: Principles and Practical Considerations
Published Online: 1 NOV 2006
Copyright © 2006 by John Wiley & Sons, Inc.
Lab Protocol Title
Current Protocols in Neuroscience
How to Cite
Kao, J. P. 2006. Caged Molecules: Principles and Practical Considerations. Current Protocols in Neuroscience. 37:6.20:6.20.1–6.20.21.
- Published Online: 1 NOV 2006
- Published Print: OCT 2006
A caged molecule is an inert but photosensitive molecule that is transformed by photolysis into a biologically active molecule at high speed (typically 1 msec). The process is referred to as photorelease. The spatial resolution of photorelease is limited by the properties of light; submicrometer resolution is potentially achievable. Therefore, focal photorelease of caged molecules enables one to control biological processes with high spatio-temporal precision. The principles underlying caged molecules as well as practical considerations for their use are discussed in this unit.
- caged molecule;
- caged compound;