UNIT 8.5A Assessment of Spatial Memory Using the Radial Arm Maze and Morris Water Maze

  1. Gary L. Wenk

Published Online: 1 MAY 2004

DOI: 10.1002/0471142301.ns0805as26

Current Protocols in Neuroscience

Current Protocols in Neuroscience

How to Cite

Wenk, G. L. 2004. Assessment of Spatial Memory Using the Radial Arm Maze and Morris Water Maze. Current Protocols in Neuroscience. 26:8.5A:8.5A.1–8.5A.12.

Author Information

  1. University of Arizona, Tucson, Arizona

Publication History

  1. Published Online: 1 MAY 2004
  2. Published Print: JAN 2004


Behavioral tasks must be evaluated in terms of the cognitive functions they require in order to be performed. All of the tasks described in this chapter can be used with each of four experimental manipulations: stimulation of a single brain region by drugs or small electrical current, impairment of normal function by production of a lesion or administration of appropriate pharmacological agents, recording of brain activity during the performance of a specific behavioral task, or behavioral phenotyping of transgenic and knockout mice for genes expressed in specific brain regions. This unit describes protocols for the radial arm maze task and the water maze task, both of which require intact spatial memory abilities.