UNIT 9.4 Preclinical Models of Parkinson's Disease

  1. Krys S. Bankiewicz1,
  2. Rosario Sanchez-Pernaute1,
  3. Yoshitsugu Oiwa1,
  4. Malgorzata Kohutnicka1,
  5. Alex Cummins2,
  6. Jamie Eberling3

Published Online: 1 MAY 2001

DOI: 10.1002/0471142301.ns0904s09

Current Protocols in Neuroscience

Current Protocols in Neuroscience

How to Cite

Bankiewicz, K. S., Sanchez-Pernaute, R., Oiwa, Y., Kohutnicka, M., Cummins, A. and Eberling, J. 2001. Preclinical Models of Parkinson's Disease. Current Protocols in Neuroscience. 9:9.4:9.4.1–9.4.32.

Author Information

  1. 1

    National Institute of Neurological Disorders and Stroke (NIH), Bethesda, Maryland

  2. 2

    National Institute of Mental Health, Bethesda, Maryland

  3. 3

    University of California Berkeley, Berkeley, California

Publication History

  1. Published Online: 1 MAY 2001
  2. Published Print: NOV 1999


Hepatic encephalopathy is a multifactorial neuropsychiatric syndrome accompanying acute or chronic liver failure. Techniques for developing animal models of hepatic encephalopathy associated with acute or chronic liver failure, or vascular shunting are illustrated. In addition, the behavioral and biochemical characteristics of these models are described.