UNIT 9.9 Animal Models of Retroviral Encephalopathies: Feline Model

  1. Michael Podell,
  2. Wayne R. Buck,
  3. Kathleen A. Hayes,
  4. Mikhail A. Gavrilin,
  5. Lawrence E. Mathes

Published Online: 1 FEB 2002

DOI: 10.1002/0471142301.ns0909s17

Current Protocols in Neuroscience

Current Protocols in Neuroscience

How to Cite

Podell, M., Buck, W. R., Hayes, K. A., Gavrilin, M. A. and Mathes, L. E. 2002. Animal Models of Retroviral Encephalopathies: Feline Model. Current Protocols in Neuroscience. 17:9.9:9.9.1–9.9.30.

Author Information

  1. The Ohio State University, Columbus, Ohio

Publication History

  1. Published Online: 1 FEB 2002
  2. Published Print: OCT 2001


Human immunodeficiency virus infection in children and adults results in a progressive neurodegenerative disease consistent with a predominant subcortical mediated dementia. Techniques for developing a feline model of the early stages of lentiviral-associated neurodegeneration are presented. The behavioral, neurophysiologic, immunologic, virologic, and neuropathologic aspects of this model are also described.