UNIT 9.14 Models of Neuropathic Pain in the Rat

  1. Gary J. Bennett1,
  2. Jin Mo Chung2,
  3. Marie Honore (Table 9.14.2)3,
  4. Ze'ev Seltzer4

Published Online: 1 MAY 2003

DOI: 10.1002/0471142301.ns0914s22

Current Protocols in Neuroscience

Current Protocols in Neuroscience

How to Cite

Bennett, G. J., Chung, J. M., Honore, M. and Seltzer, Z. 2003. Models of Neuropathic Pain in the Rat. Current Protocols in Neuroscience. 22:9.14:9.14.1–9.14.16.

Author Information

  1. 1

    McGill University, Montreal, Quebec, Canada

  2. 2

    Marine Biomedical Institute, Galveston, Texas

  3. 3

    Abbott Laborotories, Abbott Park, Illinois

  4. 4

    University of Toronto, Toronto, Ontario, Canada

Publication History

  1. Published Online: 1 MAY 2003
  2. Published Print: JAN 2003


There are now three models of neuropathic pain in the rat that are in widespread use: the chronic constriction injury, the partial sciatic ligation model, and the spinal nerve ligation model. The procedures to create these models and the behavioral assays used to quantify the resulting abnormal pain sensations are described in this unit.