UNIT 9.17 Measurement of Panic-Like Responses Following Intravenous Infusion of Sodium Lactate in Panic-Prone Rats
Published Online: 1 NOV 2003
Copyright © 2003 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Neuroscience
How to Cite
Sajdyk, T. J., Keim, S. R., Thielen, S. R., Fitz, S. D. and Shekhar, A. 2003. Measurement of Panic-Like Responses Following Intravenous Infusion of Sodium Lactate in Panic-Prone Rats. Current Protocols in Neuroscience. 24:9.17:9.17.1–9.17.19.
- Published Online: 1 NOV 2003
- Published Print: JUL 2003
This unit describes a putative animal model for panic disorder. The basic premise is that pharmacological disruption of critical brain regions implicated in the circuitry of anxiety will lead to a condition similar to that of the human disorder. A clinically relevant test, the sodium lactate challenge, is utilized to assess parallels between the human condition and this rat model.
- social interaction;
- sodium lactate;