UNIT 9.23C Sugar Bingeing in Rats

  1. Nicole M. Avena,
  2. Pedro Rada,
  3. Bartley G. Hoebel

Published Online: 1 AUG 2006

DOI: 10.1002/0471142301.ns0923cs36

Current Protocols in Neuroscience

Current Protocols in Neuroscience

How to Cite

M. Avena, N., Rada, P. and Hoebel, B. G. 2006. Sugar Bingeing in Rats. Current Protocols in Neuroscience. 36:9.23C:9.23C.1–9.23C.6.

Author Information

  1. Princeton University, Princeton, New Jersey

Publication History

  1. Published Online: 1 AUG 2006
  2. Published Print: JUL 2006


Bingeing behavior is characteristic of many eating disorders. This unit describes an animal model of sugar bingeing. This model has been used successfully to elicit behavioral and neurochemical signs of sugar dependence in rats, e.g., indices of bingeing, withdrawal, increased intake after abstinence (deprivation effect), cross-sensitization with amphetamine, and increases in dopamine release in the nucleus accumbens due to repeated bingeing.


  • sucrose;
  • eating disorder;
  • dependence;
  • food