Unit

UNIT 1.9 Synthesis of 1,5-Anhydrohexitol Building Blocks for Oligonucleotide Synthesis

  1. Irene M. Lagoja,
  2. Arnaud Marchand,
  3. Arthur Van Aerschot,
  4. Piet Herdewijn

Published Online: 1 NOV 2003

DOI: 10.1002/0471142700.nc0109s14

Current Protocols in Nucleic Acid Chemistry

Current Protocols in Nucleic Acid Chemistry

How to Cite

Lagoja, I. M., Marchand, A., Van Aerschot, A. and Herdewijn, P. 2003. Synthesis of 1,5-Anhydrohexitol Building Blocks for Oligonucleotide Synthesis. Current Protocols in Nucleic Acid Chemistry. 14:1.9:1.9.1–1.9.22.

Author Information

  1. Rega Institute for Medical Research, Leuven, Belgium

Publication History

  1. Published Online: 1 NOV 2003
  2. Published Print: SEP 2003

Abstract

This unit describes in detail, the optimized preparations of 1,5-anhydrohexitol and the 1,5-anhydrohexitol building blocks for oligonucleotide synthesis (hG, hA, hC, hT).

Keywords:

  • hexitol nucleic acid (HNA);
  • 1,5-anhydrohexitol building blocks;
  • hA;
  • hG;
  • hC;
  • hT