UNIT 3.1 Solid-Phase Supports for Oligonucleotide Synthesis
Published Online: 1 JUN 2013
Copyright © 2013 by John Wiley & Sons, Inc.
Lab Protocol Title
Current Protocols in Nucleic Acid Chemistry
How to Cite
Guzaev, A. P. 2013. Solid-Phase Supports for Oligonucleotide Synthesis. Current Protocols in Nucleic Acid Chemistry. 53:3.1:3.1.1–3.1.60.
- Published Online: 1 JUN 2013
This unit attempts to provide a reasonably complete inventory of over 280 solid supports available to oligonucleotide chemists for preparation of natural and 3′-modified oligonucleotides. Emphasis is placed on non-nucleosidic solid supports. The relationship between the structural features of linkers and their behavior in oligonucleotide synthesis and deprotection is discussed wherever the relevant observations are available. Curr. Protoc. Nucleic Acid Chem. 53:3.1.1-3.1.60. © 2013 by John Wiley & Sons, Inc.
- nucleic acid chemistry;
- solid-phase synthesis;
- molecular biology