Unit

UNIT 4.16 Chemistry of CpG DNA

  1. Ekambar R. Kandimalla,
  2. Sudhir Agrawal

Published Online: 1 MAY 2003

DOI: 10.1002/0471142700.nc0416s12

Current Protocols in Nucleic Acid Chemistry

Current Protocols in Nucleic Acid Chemistry

How to Cite

Kandimalla, E. R. and Agrawal, S. 2003. Chemistry of CpG DNA. Current Protocols in Nucleic Acid Chemistry. 12:4.16:4.16.1–4.16.14.

Author Information

  1. Hybridon, Inc., Cambridge, Massachusetts

Publication History

  1. Published Online: 1 MAY 2003
  2. Published Print: MAR 2003

Abstract

The vertebrate immune system can recognize specific pathogen-associated molecular patterns in invading microorganisms, including the unmethylated CpG dinucleotide. This unit discusses the receptors that recognize CpG motifs and important aspects of the sequence context of CpG motifs to the end of understanding and designing CpG DNA for therapeutic purposes.