Unit

UNIT 7.5 Molecular Modeling of Nucleic Acid Structure

  1. Rodrigo Galindo-Murillo,
  2. Christina Bergonzo,
  3. Thomas E. Cheatham III

Published Online: 8 OCT 2013

DOI: 10.1002/0471142700.nc0705s54

Current Protocols in Nucleic Acid Chemistry

Current Protocols in Nucleic Acid Chemistry

How to Cite

Galindo-Murillo, R., Bergonzo, C. and Cheatham, T. E. 2013. Molecular Modeling of Nucleic Acid Structure. Current Protocols in Nucleic Acid Chemistry. 54:7.5:7.5.1–7.5.13.

Author Information

  1. Department of Medicinal Chemistry, College of Pharmacy, University of Utah, Salt Lake City, Utah

Publication History

  1. Published Online: 8 OCT 2013

Abstract

This unit is the first in a series of four units covering the analysis of nucleic acid structure by molecular modeling. The unit provides an overview of the computer simulation of nucleic acids. Topics include the static structure model, computational graphics and energy models, the generation of an initial model, and characterization of the overall three-dimensional structure. Curr. Protoc. Nucleic Acid Chem. 54:7.5.1-7.5.13. © 2013 by John Wiley & Sons, Inc.

Keywords:

  • nucleic acid chemistry;
  • nucleic acid structure and folding;
  • structural analysis of biomolecules;
  • experimental determination of structure;
  • folding and conformational change