UNIT 18.1 Overview of Protein Phosphorylation

  1. Bartholomew M. Sefton1,
  2. Shirish Shenolikar2

Published Online: 1 MAY 2001

DOI: 10.1002/0471142727.mb1801s33

Current Protocols in Molecular Biology

Current Protocols in Molecular Biology

How to Cite

Sefton, B. M. and Shenolikar, S. 2001. Overview of Protein Phosphorylation. Current Protocols in Molecular Biology. 33:18.1:18.1.1–18.1.5.

Author Information

  1. 1

    The Salk Institute, San Diego, California

  2. 2

    Duke University Medical Center, Durham, North Carolina

Publication History

  1. Published Online: 1 MAY 2001
  2. Published Print: JAN 1996


This overview discusses the significance and roles of protein phosphorylation in regulation of protein function. Sites of phosphorylation are described as well as methods for detecting both radiolabeled and unlabeled phosphoamino acids. Importantly, protein kinases and phosphatases, the regulators of phosphorylation are discussed.