UNIT 9.1 Introduction to Peptide Synthesis
Published Online: 1 MAY 2002
Copyright © 2003 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Immunology
How to Cite
Fields, G. B. 2002. Introduction to Peptide Synthesis. Current Protocols in Immunology. 47:9.1:9.1.1–9.1.9.
- Published Online: 1 MAY 2002
- Published Print: FEB 2002
A number of synthetic peptides are significant commercial or pharmaceutical products, ranging from the dipeptide sugar-substitute aspartame to clinically used hormones, such as oxytocin, adrenocorticotropic hormone, and calcitonin. This unit provides an overview of the field of synthetic peptides and proteins, including their purification. It discusses selecting the solid support and common coupling reagents. Additional information is provided regarding common side reactions and synthesizing modified residues.