UNIT 11.9A Key Molecules Involved in Receptor-Mediated Lymphocyte Activation
Published Online: 1 NOV 2001
Copyright © 2003 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Immunology
How to Cite
O'Shea, J. J., Johnston, J. A., Kehrl, J., Koretzky, G. and Samelson, L. E. 2001. Key Molecules Involved in Receptor-Mediated Lymphocyte Activation. Current Protocols in Immunology. 44:11.9A:11.9A.1–11.9A.14.
- Published Online: 1 NOV 2001
- Published Print: AUG 2001
This unit, along with Unit 11.9B, provides a summary of our current knowledge about various signaling pathways critical to the function of immune cells. Here, our understanding of T cell receptor (TCR)- and B cell receptor (BCR)-mediated signaling is summarized. A schematic representation of immunologically relevant cytokine receptors and the Janus Family Kinases (JAKs) that is activated through these receptors is provided, along with details about molecules involved in interleukin 2 mediated signal transduction.