Unit

UNIT 14.12 Toll-Like Receptors

  1. Kiyoshi Takeda1,
  2. Shizuo Akira2

Published Online: 1 MAY 2007

DOI: 10.1002/0471142735.im1412s77

Current Protocols in Immunology

Current Protocols in Immunology

How to Cite

Takeda, K. and Akira, S. 2007. Toll-Like Receptors. Current Protocols in Immunology. 77:14.12:14.12.1–14.12.13.

Author Information

  1. 1

    Osaka University, Osaka, Japan

  2. 2

    Osaka University and ERATO Japan Science and Technology Agency, Osaka, Japan

Publication History

  1. Published Online: 1 MAY 2007
  2. Published Print: MAY 2007

This is not the most recent version of the article. View current version (1 APR 2015)

Abstract

This has led to the identification of several important roles for Toll receptors in mammals. This unit discusses mammalian Toll receptors (TLR1-10) that have an essential role in the innate immune recognition of microorganisms. Also discussed are TLR-mediated signaling pathways and antibodies that are available to detect specific TLRs.

Keywords:

  • innate immunity;
  • Toll-like receptors;
  • NOD;
  • RNA helicase;
  • TIR domain