Unit

UNIT 19.1 Schistosomiasis

  1. Matthew S. Tucker1,
  2. Laksiri B. Karunaratne1,
  3. Fred A. Lewis1,
  4. Tori C. Freitas2,
  5. Yung-san Liang1

Published Online: 18 NOV 2013

DOI: 10.1002/0471142735.im1901s103

Current Protocols in Immunology

Current Protocols in Immunology

How to Cite

Tucker, M. S., Karunaratne, L. B., Lewis, F. A., Freitas, T. C. and Liang, Y.-s. 2013. Schistosomiasis. Current Protocols in Immunology. 103:19.1:19.1.1–19.1.58.

Author Information

  1. 1

    Biomedical Research Institute, Rockville, Maryland

  2. 2

    Myriad RBM, Inc., Saranac Lake, New York

Publication History

  1. Published Online: 18 NOV 2013

Abstract

Schistosomiasis is the second most important parasitic disease in the world in terms of public health impact. Globally, it is estimated that the disease affects over 200 million people and is responsible for 200,000 deaths each year. The three major schistosomes infecting humans are Schistosoma mansoni, S. japonicum, and S. haematobium. Much immunological research has focused on schistosomiasis because of the pathological effects of the disease, which include liver fibrosis and bladder dysfunction. This unit covers a wide range of aspects with respect to maintaining the life cycles of these parasites, including preparation of schistosome egg antigen, maintenance of intermediate snail hosts, infection of the definitive and intermediate hosts, and others. The unit primarily focuses on S. mansoni, but also includes coverage of S. japonicum and S. haematobium life cycles. Curr. Protoc. Immunol. 103:19.1.1-19.1.58. © 2013 by John Wiley & Sons, Inc.

Keywords:

  • schistosomiasis;
  • snail;
  • mansoni;
  • japonicum;
  • haematobium