UNIT 19.5 Animal Models of Mycobacteria Infection
Published Online: 1 MAY 2001
Copyright © 2003 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Immunology
How to Cite
Orme, I. M. and Roberts, A. D. 2001. Animal Models of Mycobacteria Infection. Current Protocols in Immunology. 30:19.5:19.5.1–19.5.22.
- Published Online: 1 MAY 2001
- Published Print: APR 1999
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This unit describes the infection of mice and guinea pigs with mycobacteria via the aerogenic route, or of mice via the intravenous route, as well as necropsy methods for the determination of mycobacterial loads within target organs. Additionally, methods for cultivating mycobacteria and preparing stocks are described. The protocols outlined are primarily used for M. tuberculosis, but can also be used for the study of other opportunistic Mycobacterial species.