APPENDIX 1F Mouse Endogenous Superantigens: Ms and Mls-like Determinants Encoded by Mouse Retroviruses
Published Online: 1 MAY 2001
Copyright © 2003 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Immunology
How to Cite
Hodes, R. J. and Abe, R. 2001. Mouse Endogenous Superantigens: Ms and Mls-like Determinants Encoded by Mouse Retroviruses. Current Protocols in Immunology. 17:1F:A.1F.1–A.1F.5.
- Published Online: 1 MAY 2001
- Published Print: MAR 1996
Commonly used inbred mouse strains express different combinations of integrated mouse mammary tumor proviruses (MMTV). This appendix summarizes the proviruses that have been detected. The reported functional properties of those MMTV proviral products which have been identified as superantigens are also summarized, including the ability to elicit primary or secondary T cell responses and to induce Vb-specific clonal deletion during T cell differentiation. In addition, the amino acid sequences of putative ORF gene products of different MMTV are compared.