APPENDIX 4B Monoclonal Antibodies to Mouse Cell-Surface Antigens

  1. Noosheen Alaverdi

Published Online: 1 MAY 2002

DOI: 10.1002/0471142735.ima04bs47

Current Protocols in Immunology

Current Protocols in Immunology

How to Cite

Alaverdi, N. 2002. Monoclonal Antibodies to Mouse Cell-Surface Antigens. Current Protocols in Immunology. 62:4B:A.4B.1–A.4B.25.

Author Information

  1. eBioscience, Inc., San Diego, California

Publication History

  1. Published Online: 1 MAY 2002
  2. Published Print: FEB 2002


The cluster of differentiation (CD) nomenclature, originally devised by the International Workshop on Human Leukocyte Differentiation Antigens (HLDA) to classify leukocyte surface antigens, has become more accepted by researchers in nonhuman animal models. The CD homologues from other species are usually identified by multiple studies, including biochemical, functional analysis, cloning, and immunological assays. This unit compiles a complete (as of August, 2001) list of monoclonal antibodies (mAb) to the mouse CD antigens and several non-CD surface antigens that are commonly used as phenotypic and functional markers in the mouse system. There are many reagents recognizing polymorphic epitopes of the mouse MHC and different subunits of TCR; for simplicity, only a few mAbs to the framework determinants of these molecules are listed here.