Unit

UNIT 1.1 Collection of Clinical and Epidemiological Data for Linkage Studies

  1. Lindsay Farrer

Published Online: 1 MAY 2004

DOI: 10.1002/0471142905.hg0101s40

Current Protocols in Human Genetics

Current Protocols in Human Genetics

How to Cite

Farrer, L. 2004. Collection of Clinical and Epidemiological Data for Linkage Studies. Current Protocols in Human Genetics. 40:1.1:1.1.1–1.1.17.

Author Information

  1. Boston University School of Medicine and Harvard Medical School, Boston, Massachusetts

Publication History

  1. Published Online: 1 MAY 2004
  2. Published Print: JAN 2004

This is not the most recent version of the article. View current version (1 JAN 2012)

Abstract

Accurate assessment of the genetic basis for a disorder is necessary to determine if linkage studies will be meaningful. This unit provides an overview of key concepts and presents guidelines for collecting diagnostic, epidemiological, and genealogical data from potential study participants. The commentary discusses methods for evaluating evidence of genetic versus environmental influences in a disease and for assessing individual pedigrees.