UNIT 1.8 Model-Free Tests for Genetic Linkage

  1. Christopher I. Amos

Published Online: 1 MAY 2001

DOI: 10.1002/0471142905.hg0108s28

Current Protocols in Human Genetics

Current Protocols in Human Genetics

How to Cite

Amos, C. I. 2001. Model-Free Tests for Genetic Linkage. Current Protocols in Human Genetics. 28:1.8:1.8.1–1.8.31.

Author Information

  1. University of Texas, Houston, Texas

Publication History

  1. Published Online: 1 MAY 2001
  2. Published Print: FEB 2001

This is not the most recent version of the article. View current version (1 OCT 2012)


This unit covers statistical methods of linkage analysis that do not require assuming a detailed genetic model as is required for standard lod score analysis. The unit has been updated to include the latest methods in sib-pair analysis as well as relative- pair analysis, including the NPL method used in GENEHUNTER and GENEHUNTER PLUS.