UNIT 4.8 Chromosome Microdissection
Published Online: 1 MAY 2001
Copyright © 2003 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Human Genetics
How to Cite
Meltzer, P. and Bittner, M. 2001. Chromosome Microdissection. Current Protocols in Human Genetics. 14:4.8:4.8.1–4.8.17.
- Published Online: 1 MAY 2001
- Published Print: AUG 1997
This unit describes chromosome microdissection methodologies that are useful in both clinical and research laboratories. In combination with FISH, region-specific probes can be made to determine the origin of marker chromosomes. Another application of the microdissection technology is in the generation of regionspecific cDNA libraries, known as microdissection-mediated cDNA capture.