UNIT 8.2 Quality Assurance and Quality Control in Clinical Cytogenetics

  1. Michael S. Watson

Published Online: 1 OCT 2007

DOI: 10.1002/0471142905.hg0802s55

Current Protocols in Human Genetics

Current Protocols in Human Genetics

How to Cite

Watson, M. S. 2007. Quality Assurance and Quality Control in Clinical Cytogenetics. Current Protocols in Human Genetics. 55:8.2:8.2.1–8.2.9.

Author Information

  1. American College of Medical Genetics, Bethesda, Maryland

Publication History

  1. Published Online: 1 OCT 2007
  2. Published Print: OCT 2007

This is not the most recent version of the article. View current version (14 JUL 2014)


The goal of any clinical laboratory should be to provide patients with the most accurate test results possible. This is accomplished through various overlapping programs that continuously monitor and optimize all aspects of a test, including decisions by the laboratory to offer a test, the decision of providers to request the test, the testing itself, and the reporting of results to the referral source and patient. The levels at which test performance and accuracy can be optimized are encompassed under quality control (QC) and quality assurance (QA). The monitoring of QC and QA problems allows for the integration of these parameters into a total quality management program. This unit reviews QC and QA guidelines, in addition to discussing how to establish a quality assurance program. Curr. Protoc. Hum. Genet. 55:8.2.1-8.2.9. © 2007 by John Wiley & Sons, Inc.


  • healthcare quality assurance;
  • cytogenetics;
  • genetic testing