Unit

UNIT 8.10 Diagnosis of Cryptic Chromosomal Syndromes by Fluorescence In Situ Hybridization (FISH)

  1. Catherine D. Kashork,
  2. Aaron Theisen,
  3. Lisa G. Shaffer

Published Online: 1 OCT 2010

DOI: 10.1002/0471142905.hg0810s67

Current Protocols in Human Genetics

Current Protocols in Human Genetics

How to Cite

Kashork, C. D., Theisen, A. and Shaffer, L. G. 2010. Diagnosis of Cryptic Chromosomal Syndromes by Fluorescence In Situ Hybridization (FISH). Current Protocols in Human Genetics. 67:8.10:8.10.1–8.10.20.

Author Information

  1. Signature Genomic Laboratories, Spokane, Washington

Publication History

  1. Published Online: 1 OCT 2010
  2. Published Print: OCT 2010

Abstract

This unit describes the various methods by which cytogeneticists detect chromosome abnormalities. The unit offers guidance for detecting such abnormalities with fluorescence in situ hybridization (FISH), as well as the benefits, limitations, and other applications of FISH. Curr. Protoc. Hum. Genet. 67:8.10.1-8.10.20 © 2010 by John Wiley & Sons, Inc.

Keywords:

  • FISH;
  • cytogenetics;
  • chromosomal abnormalities