Unit

UNIT 9.21 The Application of Computer-Based Tools in Obtaining the Genetic Family History

  1. Monica A. Giovanni,
  2. Michael F. Murray

Published Online: 1 JUL 2010

DOI: 10.1002/0471142905.hg0921s66

Current Protocols in Human Genetics

Current Protocols in Human Genetics

How to Cite

Giovanni, M. A. and Murray, M. F. 2010. The Application of Computer-Based Tools in Obtaining the Genetic Family History. Current Protocols in Human Genetics. 66:9.21:9.21.1–9.21.9.

Author Information

  1. Brigham and Women's Hospital, Boston, Massachusetts

Publication History

  1. Published Online: 1 JUL 2010
  2. Published Print: JUL 2010

Abstract

Family health history is both an adjunct to and a focus of current genetic research, having long been known to be a powerful predictor of individual disease risk. As such, it has been primarily used as a proxy for genetic information. Over the past decade, new roles for family history have emerged, perhaps most importantly as a primary tool for guiding decision-making on the use of expensive genetic testing. The collection of family history information is an important but time-consuming process. Efforts to engage the patient or research subject in preliminary data collection have the potential to improve data accuracy and allow clinicians and researchers more time for analytic tasks. The U.S. Surgeon General, the Centers for Disease Control and Prevention (CDC), and others have developed tools for electronic family history collection. This unit describes the utility of the Web-based My Family Health Portrait (https://familyhistory.hhs.gov) as the prototype for patient-entered family history. Curr. Protoc. Hum. Genet. 66:9.21.1-9.21.9 © 2010 by John Wiley & Sons, Inc.

Keywords:

  • family history;
  • pedigree;
  • risk assessment;
  • genetic medicine