UNIT 8.7 Combination DNA/RNA Fish and Immunophenotyping

  1. Roeland W. Dirks

Published Online: 1 MAY 2001

DOI: 10.1002/0471142956.cy0807s06

Current Protocols in Cytometry

Current Protocols in Cytometry

How to Cite

Dirks, R. W. 2001. Combination DNA/RNA Fish and Immunophenotyping. Current Protocols in Cytometry. 6:8.7:8.7.1–8.7.14.

Author Information

  1. Leiden University Medical Centre, Leiden, The Netherlands

Publication History

  1. Published Online: 1 MAY 2001
  2. Published Print: OCT 1998


This unit presents methods for combining immunophenotyping with DNA/RNA FISH. The approach is used in so-called genotype/phenotype analysis to identify chromosomal aberrations in sub-populations of cells present in heterogenous populations. Combining RNA and DNA detection with identification of cellular proteins is quite difficult. This series of protocols is provided to enable the successful application of the combination of these techniques.