UNIT 11.7 Mycobacterium tuberculosis Susceptibility Testing by Flow Cytometry

  1. Ronald F. Schell1,
  2. Dean T. Nardelli1,
  3. David J. DeCoster1,
  4. Scott M. Kirk2,
  5. Steven M. Callister3

Published Online: 1 FEB 2004

DOI: 10.1002/0471142956.cy1107s27

Current Protocols in Cytometry

Current Protocols in Cytometry

How to Cite

Schell, R. F., Nardelli, D. T., DeCoster, D. J., Kirk, S. M. and Callister, S. M. 2004. Mycobacterium tuberculosis Susceptibility Testing by Flow Cytometry. Current Protocols in Cytometry. 27:11.7:11.7.1–11.7.8.

Author Information

  1. 1

    University of Wisconsin, Madison, Wisconsin

  2. 2

    Amersham Biosciences, Sunnyvale, California

  3. 3

    Gundersen Lutheran Medical Center, LaCrosse, Wisconsin

Publication History

  1. Published Online: 1 FEB 2004
  2. Published Print: JAN 2004


Here is another unit with clinical relevance. Tuberculosis remains a major health problem throughout the world, with approximately one-quarter of the population being infected. Rapid and accurate susceptibility testing for the tubercle bacillus is essential for control of the disease. Such testing can be accomplished by flow cytometry within twenty-four hours, instead of the days to weeks required by traditional methods. The use of flow cytometry both improves the quality of susceptibility testing and advances public health measures for the prevention and control of this ancient scourge.


  • flow cytometry;
  • Mycobacterium tuberculosis;
  • susceptibility testing;
  • tuberculosis;
  • public health