Unit

UNIT 12.11 Confocal Imaging of Cell Division

  1. Paul S. Maddox

Published Online: 1 JAN 2008

DOI: 10.1002/0471142956.cy1211s43

Current Protocols in Cytometry

Current Protocols in Cytometry

How to Cite

Maddox, P. S. 2008. Confocal Imaging of Cell Division. Current Protocols in Cytometry. 43:12.11:12.11.1–12.11.13.

Author Information

  1. Department of Pathology and Cell Biology, Université de Montréal, Montreal, Canada

Publication History

  1. Published Online: 1 JAN 2008
  2. Published Print: JAN 2008

Abstract

Imaging of subcellular events has been key to recent advances in the basic knowledge base as well as drug discovery for disease states such as cancer. In a snowball effect, advances in imaging have spurred new investigations, which have increased the demand for new technologies. The study of cell division serves as an example of this cycle. Here, application of spinning disk confocal technology to the study of cell division is discussed. While these studies have increased understanding of fundamental mechanisms in several mitotic events, new imaging technologies in the future will unlock more secrets of cell biology. Curr. Protocol. Cytom. 43:12.11.1-12.11.13. © 2008 by John Wiley & Sons, Inc.

Keywords:

  • confocal imaging;
  • live cell imaging;
  • mitosis;
  • cell division;
  • microtubule;
  • kinetochore;
  • chromosome condensation;
  • cytokinesis