UNIT 8.1 Overview of the Cell Cycle
Published Online: 1 MAY 2001
Copyright © 2003 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Cell Biology
How to Cite
Park, M. S. and Koff, A. 2001. Overview of the Cell Cycle. Current Protocols in Cell Biology. 00:8.1:8.1.1–8.1.9.
- Published Online: 1 MAY 2001
- Published Print: OCT 1998
Progression through the cell cycle is regulated by inductive signals from outside the cell and intracellular signal pathways, while the cycle itself is regulated by cyclin-dependent kinases (CDKs). An understanding of the functions of these molecules is necessary to understand the processes of mitosis, differentiation, senescence, apoptosis, and tumorigenesis. This overview reviews the current state of knowledge for the biology of the cell-cycle, the CDKs, the role of proteolysis, targets of the cell cycle machinery, and a paradigm of cell cycle analysis.