UNIT 10.1 Overview of Extracellular Matrix

  1. Robert P. Mecham

Published Online: 1 MAY 2001

DOI: 10.1002/0471143030.cb1001s00

Current Protocols in Cell Biology

Current Protocols in Cell Biology

How to Cite

Mecham, R. P. 2001. Overview of Extracellular Matrix. Current Protocols in Cell Biology. 00:10.1:10.1.1–10.1.14.

Author Information

  1. Washington University School of Medicine, St. Louis, Missouri

Publication History

  1. Published Online: 1 MAY 2001
  2. Published Print: OCT 1998

This is not the most recent version of the article. View current version (1 DEC 2012)


The extracellular matrix provides an environment for cells. It is produced, assembled and modified by cells and in turn, it modifies the functions and behavior of the cells it encounters. The molecules that make up the matrix are diverse in both structure and function. This well-illustrated unit provides an introduction to the structure and function of the major components of matrix and serves as a background for the other units in the chapter which include protocols for isolation and analysis of individual components.