UNIT 10.1 Overview of Extracellular Matrix

  1. Robert P. Mecham

Published Online: 1 DEC 2012

DOI: 10.1002/0471143030.cb1001s57

Current Protocols in Cell Biology

Current Protocols in Cell Biology

How to Cite

Mecham, R. P. 2012. Overview of Extracellular Matrix. Current Protocols in Cell Biology. 57:10.1:10.1.1–10.1.16.

Author Information

  1. Washington University School of Medicine, St. Louis, Missouri

Publication History

  1. Published Online: 1 DEC 2012
  2. Published Print: DEC 2012


The extracellular matrix provides an environment for cells. It is produced, assembled, and modified by cells and in turn, it modifies the functions and behavior of the cells it encounters. The molecules that make up the matrix are diverse in both structure and function. This well-illustrated unit provides an introduction to the structure and function of the major components of the extracellular matrix and serves as a background for the other units in the chapter, which include protocols for isolation and analysis of individual components. Curr. Protoc. Cell Biol. 57:10.1.1-10.1.16. © 2012 by John Wiley & Sons, Inc.


  • cell biology;
  • extracellular matrix;
  • adhesion