UNIT 12.3 Cell Traction

  1. Catherine G. Galbraith,
  2. Michael P. Sheetz

Published Online: 1 MAY 2001

DOI: 10.1002/0471143030.cb1203s00

Current Protocols in Cell Biology

Current Protocols in Cell Biology

How to Cite

Galbraith, C. G. and Sheetz, M. P. 2001. Cell Traction. Current Protocols in Cell Biology. 00:12.3:12.3.1–12.3.16.

Author Information

  1. Duke University Medical Center, Durham, North Carolina

Publication History

  1. Published Online: 1 MAY 2001
  2. Published Print: OCT 1998


Traction forces are exerted by cells on their substratum as they migrate. These forces under the entire cell or subcellular regions can be measured. This unit describes several protocols for making silicone sheets to measure traction forces under the entire cell, as well as a protocol for developing a micromachined device to measure forces under subcellular regions.