UNIT 19.7 Imaging Tumor Cell Movement In Vivo
Published Online: 1 JUN 2007
Copyright © 2007 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Cell Biology
How to Cite
Kedrin, D., Wyckoff, J., Sahai, E., Condeelis, J. and Segall, J. E. 2007. Imaging Tumor Cell Movement In Vivo. Current Protocols in Cell Biology. 35:19.7:19.7.1–19.7.17.
- Published Online: 1 JUN 2007
- Published Print: JUN 2007
This is not the most recent version of the article. View current version (1 MAR 2013)
This unit describes the methods that we have been developing for analyzing tumor cell motility in mouse and rat models of breast cancer metastasis. Rodents are commonly used to provide a mammalian system for studying human tumor cells as xenografts in immunocompromised mice, as well as for following the development of tumors from a specific tissue type in transgenic lines. The Basic Protocol describes the standard methods used for generation of mammary tumors and imaging them. Additional protocols for labeling macrophages, blood vessel imaging, and image analysis are also included.
- mammary tumor;
- image analysis