UNIT 22.8 Detection of Mitotic Figures and Components of the Mitotic Machinery
Published Online: 1 JAN 2005
Copyright © 2004 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Cell Biology
How to Cite
Bayani, J. and Squire, J. A. 2005. Detection of Mitotic Figures and Components of the Mitotic Machinery. Current Protocols in Cell Biology. 25:22.8:22.8.1–22.8.6.
- Published Online: 1 JAN 2005
- Published Print: DEC 2004
Mitotic figures have provided important information on the mechanisms behind observed chromosomal aberrations. Variations in cell culturing and fixation methods enhance the visualization of mitotic figures. Furthermore, immunohistochemistry using a host of antibodies against protein structures involved in the cell cycle, as well as against those components involved in anchoring chromosomal structures, can reveal changes in chromosomal segregation.
- mitotic figures;
- mitotic machinery;
- chromosomal segregation