Unit

UNIT 23.1 Stem Cells: An Overview

  1. Mark Denham,
  2. Brock Conley,
  3. Fredrik Olsson,
  4. Timothy J. Cole,
  5. Richard Mollard

Published Online: 1 OCT 2005

DOI: 10.1002/0471143030.cb2301s28

Current Protocols in Cell Biology

Current Protocols in Cell Biology

How to Cite

Denham, M., Conley, B., Olsson, F., Cole, T. J. and Mollard, R. 2005. Stem Cells: An Overview. Current Protocols in Cell Biology. 28:23.1:23.1.1–23.1.18.

Author Information

  1. Monash University, Melbourne, Australia

Publication History

  1. Published Online: 1 OCT 2005
  2. Published Print: SEP 2005

Abstract

Stem cells are specialized cells that possess a capacity to undergo self-renewal while at the same time having the ability to give rise to at least one or more differentiated or mature cell type. They therefore represent a fundamental cornerstone during the life of all vertebrates, playing central roles in the production of new and replacement cells for tissues during development and homeostasis, including repair following disease or injury. This unit is a review of stem cells, their roles in development, and their potentials as therapeutic agents.

Keywords:

  • Embryonic;
  • Adult;
  • Hematopoietic;
  • Mesenchymal;
  • Neural stem cell;
  • Therapy