APPENDIX 1C Identification of Motifs in Protein Sequences

  1. Erik L.L. Sonnhammer1,
  2. Tyra G. Wolfsberg2

Published Online: 1 MAY 2001

DOI: 10.1002/0471143030.cba01cs00

Current Protocols in Cell Biology

Current Protocols in Cell Biology

How to Cite

Sonnhammer, E. L. and Wolfsberg, T. G. 2001. Identification of Motifs in Protein Sequences. Current Protocols in Cell Biology. 00:1C:A.1C.1–A.1C.8.

Author Information

  1. 1

    Center for Genomics Research, Karolinska Institutet, Stockholm, Sweden

  2. 2

    National Center for Biotechnology Information/NIH, Bethesda, Maryland

Publication History

  1. Published Online: 1 MAY 2001
  2. Published Print: OCT 1998


This brief appendix serves as a guide for the analysis of functional motifs in proteins. Several database search engines that can be accessed via the World Wide Web are described. Such computerized searches have become the preferred method to scan large sequence and motif databases, as the searches are efficient and the databases are updated frequently. A short list of sorting signals is also included, since these motifs often cannot be predicted reliably by a computer search.