Chapter 15. Results and Implications of Large-Scale DNA Sequencing

  1. Charles R. Cantor and
  2. Cassandra L. Smith

Published Online: 20 JUN 2002

DOI: 10.1002/0471220566.ch15

Genomics: The Science and Technology Behind the Human Genome Project

Genomics: The Science and Technology Behind the Human Genome Project

How to Cite

Cantor, C. R. and Smith, C. L. (1999) Results and Implications of Large-Scale DNA Sequencing, in Genomics: The Science and Technology Behind the Human Genome Project, John Wiley & Sons, Inc., New York, USA. doi: 10.1002/0471220566.ch15

Author Information

  1. Center for Advanced Biotechnology, Boston University, Boston, Massachusetts

Publication History

  1. Published Online: 20 JUN 2002
  2. Published Print: 2 FEB 1999

ISBN Information

Print ISBN: 9780471599081

Online ISBN: 9780471220565

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Keywords:

  • large-scale DNA sequencing;
  • genome project;
  • costing;
  • genes;
  • sequence analysis;
  • neural net analysis;
  • errors;
  • biological function of DNA sequences;
  • biological function of genes;
  • comparing sequences;
  • dynamic programming;
  • domains;
  • motifs;
  • noncoding sequence

Summary

The authors know with certainty that much of this chapter will become obsolete in the time interval it takes to progress from completed manuscript to published textbook. This is truly an area where electronic rather than written communication must predominate. Hence, while a few examples of original projections of human genome project progress are given, and a few examples of actual progress are summarized, the emphasis is on principles that underlie the analysis of DNA sequence.