Chapter 1. Introduction
Published Online: 19 MAR 2002
DOI: 10.1002/0471221937.ch1
Copyright © 2002 by Wiley-Liss, Inc.
Book Title
Genomic Imprinting and Uniparental Disomy in Medicine: Clinical and Molecular Aspects
Additional Information
How to Cite
Engel, E. and Antonarakis, S. E. (2002) Introduction, in Genomic Imprinting and Uniparental Disomy in Medicine: Clinical and Molecular Aspects, John Wiley & Sons, Inc., New York, USA. doi: 10.1002/0471221937.ch1
Publication History
- Published Online: 19 MAR 2002
- Published Print: 15 OCT 2001
ISBN Information
Print ISBN: 9780471351269
Online ISBN: 9780471221937
- Summary
- Chapter
Keywords:
- uniparental disomy;
- isodisomy;
- heterodisomy;
- genomic imprinting
Summary
This introductory chapter includes the history of the concept and the first documented cases of uniparental disomy, an overview of the mechanisms and consequences of UPD, definitions of isodisomy and heterodisomy, a brief overview of genomic imprinting, and a discussion of the relationship between UPD and imprinting.