Chapter 19. The Role of Early B-cell Factor in B-lymphocyte Development

  1. Katya Ravid2,
  2. Jonathan D. Licht3
  1. Mikael Sigvardsson

Published Online: 19 MAR 2002

DOI: 10.1002/0471223883.ch19

Book Title

Transcription Factors: Normal and Malignant Development of Blood Cells

Transcription Factors: Normal and Malignant Development of Blood Cells

Additional Information

How to Cite

Sigvardsson, M. (2002) The Role of Early B-cell Factor in B-lymphocyte Development, in Transcription Factors: Normal and Malignant Development of Blood Cells (eds K. Ravid and J. D. Licht), John Wiley & Sons, Inc., New York, USA. doi: 10.1002/0471223883.ch19

Editor Information

  1. 2

    Department of Biochemistry, Boston University School of Medicine, Boston, MA

  2. 3

    Derald H. Ruttenberg Cancer Center and Department of Medicine, Mount Sinai School of Medicine, New York, NY

Author Information

  1. Lund University, The Department of Stem Cell Biology, Lund S-221 07, Sweden

Publication History

  1. Published Online: 19 MAR 2002
  2. Published Print: 15 DEC 2000

ISBN Information

Print ISBN: 9780471350545

Online ISBN: 9780471223887

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Keywords:

  • early B-cell factor (EBF);
  • B-lymphocyte development;
  • genetic targets

Summary

EBF belongs to an evolutionary conserved family of proteins involved in the development of specific structures or cell lineages. The focus of this chapter is the role of EBF in B-cell development, where the work from several laboratories has allowed for the identification of several genetic targets and interaction partners, making EBF one of the best-characterized transcription factors in early B-cell development.

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