Chapter 30. NF-κB in Cell Life and Death
- Katya Ravid2,
- Jonathan D. Licht3
Published Online: 19 MAR 2002
DOI: 10.1002/0471223883.ch30
Copyright © 2001 by Wiley-Liss, Inc.
Book Title
Transcription Factors: Normal and Malignant Development of Blood Cells
Additional Information
How to Cite
Tam, W. F., Sen, J. and Sen, R. (2002) NF-κB in Cell Life and Death, in Transcription Factors: Normal and Malignant Development of Blood Cells (eds K. Ravid and J. D. Licht), John Wiley & Sons, Inc., New York, USA. doi: 10.1002/0471223883.ch30
Editor Information
- 2
Department of Biochemistry, Boston University School of Medicine, Boston, MA
- 3
Derald H. Ruttenberg Cancer Center and Department of Medicine, Mount Sinai School of Medicine, New York, NY
Publication History
- Published Online: 19 MAR 2002
- Published Print: 15 DEC 2000
ISBN Information
Print ISBN: 9780471350545
Online ISBN: 9780471223887
- Summary
- Chapter
Keywords:
- NF-κB family;
- I-κB family;
- NF-κB function;
- Rel gene knockouts;
- cell cycle;
- cell viability;
- antiapoptotic genes;
- proapoptotic activity;
- cancer
Summary
Rational manipulation of NF-κB function is likely to be beneficial in diverse circumstances. In this chapter the authors review recent studies that address the mechanisms that link Rel proteins to the control of cell proliferation and cell death.