Chapter 31. Transcription Factors Implicated in Hematopoiesis: In Vivo Studies

  1. Katya Ravid2,
  2. Jonathan D. Licht3
  1. Yulia Kaluzhny1,
  2. Katya Ravid2

Published Online: 19 MAR 2002

DOI: 10.1002/0471223883.ch31

Transcription Factors: Normal and Malignant Development of Blood Cells

Transcription Factors: Normal and Malignant Development of Blood Cells

How to Cite

Kaluzhny, Y. and Ravid, K. (2002) Transcription Factors Implicated in Hematopoiesis: In Vivo Studies, in Transcription Factors: Normal and Malignant Development of Blood Cells (eds K. Ravid and J. D. Licht), John Wiley & Sons, Inc., New York, USA. doi: 10.1002/0471223883.ch31

Editor Information

  1. 2

    Department of Biochemistry, Boston University School of Medicine, Boston, MA

  2. 3

    Derald H. Ruttenberg Cancer Center and Department of Medicine, Mount Sinai School of Medicine, New York, NY

Author Information

  1. 1

    Boston University School of Medicine, Department of Biochemistry, Whitaker Cardiovascular Institute, 115 Albany Street, Boston, MA 02118

  2. 2

    Department of Biochemistry, Boston University School of Medicine, Boston, MA

Publication History

  1. Published Online: 19 MAR 2002
  2. Published Print: 15 DEC 2000

ISBN Information

Print ISBN: 9780471350545

Online ISBN: 9780471223887

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Keywords:

  • transcription factors;
  • hematopoiesis;
  • in vivo studies

Summary

This chapter summarizes in vivo studies focusing on the role of transcription factors in hematopoiesis and in mouse development. It includes in tabular form a synopsis of all the transcription factors surveyed, their protein family, consensus binding sites and expression pattern. It also summarizes studies, described up to now, involving the use of knock-out mice to explore the role of these transcription factors in normal and malignant development of different blood cell lineages.