Chapter 14. Phylogenetic Analysis

  1. Andreas D. Baxevanis3 and
  2. B. F. Francis Ouellette4
  1. Fiona S. L. Brinkman1 and
  2. Detlef D. Leipe2

Published Online: 11 JAN 2002

DOI: 10.1002/0471223921.ch14

Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins, Volume 43, Second Edition

Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins, Volume 43, Second Edition

How to Cite

Brinkman, F. S. L. and Leipe, D. D. (2001) Phylogenetic Analysis, in Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins, Volume 43, Second Edition (eds A. D. Baxevanis and B. F. F. Ouellette), John Wiley & Sons, Inc., New York, USA. doi: 10.1002/0471223921.ch14

Editor Information

  1. 3

    Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland

  2. 4

    Centre for Molecular Medicine and Therapeutics, Children's and Women's Health Centre of British Columbia, University of British Columbia Vancouver, British Columbia, Canada

Author Information

  1. 1

    Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada

  2. 2

    National Center for Biotechnology Information,, National Library of Medicine, National Institutes of Health, Bethesda, Maryland

Publication History

  1. Published Online: 11 JAN 2002
  2. Published Print: 20 APR 2001

ISBN Information

Print ISBN: 9780471383901

Online ISBN: 9780471223924

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Keywords:

  • phylogenetic models;
  • tree interpretation;
  • paralogs;
  • orthologs;
  • phylogenetic data analysis;
  • alignment;
  • substitution model;
  • tree building;
  • distance;
  • parsimony;
  • maximum likelihood;
  • tree evaluation;
  • software

Summary

This chapter discusses methods used to infer evolutionary distance and how such information can be applied to biological problems. Some simple practical considerations are included.