Chapter 19. Clinical Applications of Gene Therapy: Cardiovascular Disease

  1. Peter J. Quesenberry2,
  2. Gary S. Stein2,
  3. Bernard G. Forget3,
  4. Sherman M. Weissman3
  1. Jonathan C. Fox

Published Online: 13 MAY 2002

DOI: 10.1002/0471223956.ch19

Book Title

Stem Cell Biology and Gene Therapy

Stem Cell Biology and Gene Therapy

Additional Information

How to Cite

Fox, J. C. (2002) Clinical Applications of Gene Therapy: Cardiovascular Disease, in Stem Cell Biology and Gene Therapy (eds P. J. Quesenberry, G. S. Stein, B. G. Forget and S. M. Weissman), John Wiley & Sons, Inc., New York, USA. doi: 10.1002/0471223956.ch19

Editor Information

  1. 2

    University of Massachusetts, Worcester, Massachusetts

  2. 3

    Yale University School of Medicine, New Haven, Connecticut

Author Information

  1. University of Pennsylvania, Department of Medicine, Room 809c, Stellar-Chance Laboratories, 422 Curie Boulevard, Philadelphia, PA 19104–6100

Publication History

  1. Published Online: 13 MAY 2002
  2. Published Print: 27 AUG 1998

ISBN Information

Print ISBN: 9780471146568

Online ISBN: 9780471223955

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Keywords:

  • cardiovascular disease;
  • gene therapy;
  • clinical applications;
  • molecular mechanisms;
  • vector systems;
  • therapeutic gene transfer;
  • specific organs

Summary

The goals of this chapter are to outline the rationale for gene therapy strategies targeting cardiovascular diseases, give an overview of the major gene transfer technologies currently applied to the cardiovascular system, and review some current approaches to in vivo genetic manipulation in the development of therapeutic strategies for cardiovascular disease.

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