Chapter 4. Stem Cell Transcription

  1. Peter J. Quesenberry2,
  2. Gary S. Stein2,
  3. Bernard G. Forget3,
  4. Sherman M. Weissman3
  1. Sherman M. Weissman3,
  2. Archibald S. Perkins1

Published Online: 13 MAY 2002

DOI: 10.1002/0471223956.ch4

Book Title

Stem Cell Biology and Gene Therapy

Stem Cell Biology and Gene Therapy

Additional Information

How to Cite

Weissman, S. M. and Perkins, A. S. (2002) Stem Cell Transcription, in Stem Cell Biology and Gene Therapy (eds P. J. Quesenberry, G. S. Stein, B. G. Forget and S. M. Weissman), John Wiley & Sons, Inc., New York, USA. doi: 10.1002/0471223956.ch4

Editor Information

  1. 2

    University of Massachusetts, Worcester, Massachusetts

  2. 3

    Yale University School of Medicine, New Haven, Connecticut

Author Information

  1. 1

    Departments of Medicine, Human Genetics, and Pathology, Yale University School of Medicine, 336 BCMM, 295 Congress Avenue, New Haven, CT 06510

  2. 3

    Yale University School of Medicine, New Haven, Connecticut

Publication History

  1. Published Online: 13 MAY 2002
  2. Published Print: 27 AUG 1998

ISBN Information

Print ISBN: 9780471146568

Online ISBN: 9780471223955

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Keywords:

  • stem cells;
  • transcription factors;
  • stem cell regulation;
  • hematopoiesis;
  • transcriptional regulation

Summary

The focus of this chapter is to encapsulate recent advances as relevant to the question of what defines a stem cell: How is a stem cell population generated? How is it maintained? How do cells depart from the stem cell pool into committed derivatives? The authors focus on the hematopoietic system, since it is one about which a good deal is known, and draw upon others as needed.

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