Chapter 5. Hematopoietic Stem Cells: Proliferation, Purification, and Clinical Applications

  1. Peter J. Quesenberry3,
  2. Gary S. Stein3,
  3. Bernard G. Forget4,
  4. Sherman M. Weissman4
  1. Ruth Pettengell1,
  2. Malcolm A. S. Moore2

Published Online: 13 MAY 2002

DOI: 10.1002/0471223956.ch5

Book Title

Stem Cell Biology and Gene Therapy

Stem Cell Biology and Gene Therapy

Additional Information

How to Cite

Pettengell, R. and Moore, M. A. S. (2002) Hematopoietic Stem Cells: Proliferation, Purification, and Clinical Applications, in Stem Cell Biology and Gene Therapy (eds P. J. Quesenberry, G. S. Stein, B. G. Forget and S. M. Weissman), John Wiley & Sons, Inc., New York, USA. doi: 10.1002/0471223956.ch5

Editor Information

  1. 3

    University of Massachusetts, Worcester, Massachusetts

  2. 4

    Yale University School of Medicine, New Haven, Connecticut

Author Information

  1. 1

    Department of Hematology, St. George's Hospital Medical School, Cranmer Terrace, London SW17 ORE, United Kingdom

  2. 2

    James Ewing Laboratory of Developmental Hematopoiesis, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021

Publication History

  1. Published Online: 13 MAY 2002
  2. Published Print: 27 AUG 1998

ISBN Information

Print ISBN: 9780471146568

Online ISBN: 9780471223955

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CHAPTER TOOLS

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Keywords:

  • stem cells;
  • assays;
  • phenotypes;
  • proliferation;
  • separation devices;
  • purification;
  • hematopoiesis;
  • stromal cells;
  • hematopoietic progenitor cells;
  • ex vivo HPC expansion;
  • clinical applications

Summary

In this chapter the authors review progress in the identification, mobilization, isolation, and culture of different hematopoietic progenitor subgroups and discuss their potential applications.

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