Published Online: 13 JAN 2012
Copyright © 2001 by John Wiley & Sons, Inc.
Kirk-Othmer Encyclopedia of Chemical Technology
How to Cite
Muller, T. and Bräse, S. 2012. Azides. Kirk-Othmer Encyclopedia of Chemical Technology. 1–21.
- Published Online: 13 JAN 2012
Inorganic and organic azides (RN
Although azides are multipurpose compounds in chemistry and beyond, their laboratory and especially their industrial production have always been limited by their acute toxicity and their explosive nature. A lot of inorganic and organic azides are indeed highly toxic and their more or less pronounced tendency to liberate nitrogen gas (N
Regardless of the health and safety issues, azides have never been completely abandoned by the scientific community and have known several revivals during their 150 years old history. Whenever dealing with azides, one should however always bear in mind their potential toxicity and explosive tendency and handle them accordingly.
Keywords: Azide; Staudinger reaction and ligation; Schmidt rearrangement; Curtius rearrangement; aza-Wittig; Click Chemistry; Cycloadditions